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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYPN All Species: 17.88
Human Site: S351 Identified Species: 49.17
UniProt: Q86TC9 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86TC9 NP_115967.2 1320 145257 S351 S N I Y G T D S T S A E I Y I
Chimpanzee Pan troglodytes XP_001152308 1106 122026 P223 S A S A S Q S P T E D Q G E M
Rhesus Macaque Macaca mulatta XP_001082273 1107 122073 P224 N A S A S Q S P T E D Q G E M
Dog Lupus familis XP_546131 1322 144963 S351 S N I Y G T D S T S A E I Y I
Cat Felis silvestris
Mouse Mus musculus Q5DTJ9 1315 144095 S349 S N I Y G T D S T S A E I Y I
Rat Rattus norvegicus P0C5E3 603 66686
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508648 1251 135560 C346 K P R I R W F C E G K E L Q N
Chicken Gallus gallus XP_421565 1328 146338 S355 S N I Y G T D S T S A E I Y I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_700400 2113 232632 S557 S N F Y G T D S T S A E I Y I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.7 36.7 92.9 N.A. 87.5 27.4 N.A. 30.1 67.3 N.A. 36.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 52.7 51.9 95.3 N.A. 92.4 35.9 N.A. 46.8 79.1 N.A. 46.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 13.3 6.6 100 N.A. 100 0 N.A. 6.6 100 N.A. 93.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 26.6 100 N.A. 100 0 N.A. 13.3 100 N.A. 93.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 23 0 23 0 0 0 0 0 0 56 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 56 0 0 0 23 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 12 23 0 67 0 23 0 % E
% Phe: 0 0 12 0 0 0 12 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 56 0 0 0 0 12 0 0 23 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 45 12 0 0 0 0 0 0 0 0 56 0 56 % I
% Lys: 12 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 23 % M
% Asn: 12 56 0 0 0 0 0 0 0 0 0 0 0 0 12 % N
% Pro: 0 12 0 0 0 0 0 23 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 23 0 0 0 0 0 23 0 12 0 % Q
% Arg: 0 0 12 0 12 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 67 0 23 0 23 0 23 56 0 56 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 56 0 0 78 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 56 0 0 0 0 0 0 0 0 0 56 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _